Researchers explain the organization of DNA in chromosomes from repetitive interactions between nucleosomes

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A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar organization of DNA, proposed from previous experimental research, is fully compatible with the structural and functional properties of chromosomes. This organization can be explained by weak interactions between nucleosomes, which are the repetitive blocks that fold the DNA double helix.

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